Peptide Nasal Sprays

What are Peptide Nasal Sprays?

Peptide nasal sprays have gained popularity in the research world for their approach to overcoming the challenges associated with traditional peptide delivery methods in clinical settings. Peptides, researched for their therapeutic potential, face hurdles such as low metabolic stability and poor penetration of the blood-brain barrier (BBB) in subjects, limiting their clinical utility. 

However, nasal-to-brain (N-to-B) delivery presents a promising alternative in clinical settings. Studies are examining its potential to interact with the olfactory and trigeminal nerves. This makes research into peptide nasal sprays very unique as it may potentially provide a direct pathway to the brain of subjects, circumventing the BBB and minimizing systemic exposure. This potential non-invasive method allows for rapid targeting of the central nervous system (CNS) in subjects and offers greater convenience compared to traditional clinical methods. Thus, peptide nasal sprays hold immense potential in enhancing the therapeutic efficacy of peptides by improving their bioavailability and duration of action. [R]