Triptorelin (GnRH)


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Triptorelin (GnRH) Vials

Triptorelin (GnRH) Peptide
CAS Number 57773-63-4
Molar Mass 1311.4 g/mol
Chemical Formula C64H82N18O13
IUPAC Name L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolyl-glycinamide


Triptorelin, a research peptide, falls under the category of Gonadotropin-Releasing Hormone (GnRH) analogs. Dedicated to laboratory and research purposes, Triptorelin is designed to explore its effects on reproductive endocrinology.

Key Characteristics

Triptorelin, known for its potent actions on the endocrine system, is a synthetic decapeptide analog of natural GnRH. This peptide is carefully crafted for controlled laboratory experiments, aiming to unravel its impact on reproductive hormones and related pathways.

Research Applications

The primary application of Triptorelin in research lies in its influence on the hypothalamic-pituitary-gonadal (HPG) axis. Researchers can utilize this peptide to investigate the regulation of sex hormones and the subsequent effects on reproductive processes.

Research Benefits

Decreases Testosterone Production

Triptorelin has been studied for its ability to decrease testosterone production. This aspect opens avenues for research exploring the modulation of androgen levels and its potential applications in conditions where testosterone reduction is desired.

Lowers Luteinizing Hormone and Follicular Stimulating Hormone Levels

Research suggests that Triptorelin may lower luteinizing hormone (LH) and follicular stimulating hormone (FSH) levels. This observation prompts further investigation into the peptide’s role in modulating key reproductive hormones.

Triptorelin and Fertility

Triptorelin’s impact on fertility is an intriguing area of research. Studies indicate potential applications in fertility-related investigations, including the exploration of assisted reproductive technologies.


In summary, Triptorelin (GnRH) Peptide offers researchers a valuable tool to delve into the intricacies of the HPG axis. With benefits encompassing the modulation of testosterone production, reduction of LH and FSH levels, and potential implications for fertility, Triptorelin holds promise for advancing our understanding of reproductive endocrinology.


  1. Breul J, Lundström E, Purcea D, Venetz WP, Cabri P, Dutailly P, Goldfischer ER. Efficacy of Testosterone Suppression with Sustained-Release Triptorelin in Advanced Prostate Cancer. Adv Ther. 2017 Feb;34(2):513-523. doi: 10.1007/s12325-016-0466-7. Epub 2016 Dec 27. PMID: 28028737; PMCID: PMC5331090. [Read More].
  2. Xie M, Yu H, Zhang X, Wang W, Ren Y. Elasticity of adenomyosis is increased after GnRHa therapy and is associated with spontaneous pregnancy in infertile patents. J Gynecol Obstet Hum Reprod. 2019 Dec;48(10):849-853. doi: 10.1016/j.jogoh.2019.05.003. Epub 2019 May 5. PMID: 31067498. [Read More].


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