7,8 Dihydroxyflavone


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7,8 Dihydroxyflavone Powder

7.8 Dihydroxyflavone 
CAS Number 38183-03-8
Molar Mass 254.241 g·mol−1
Chemical Structure C15H10O4
IUPAC Name 7,8-Dihydroxy-2-phenyl-4H-chromen-4-one


7,8 Dihydroxyflavone is a research compound of notable interest, exclusively intended for research applications and not intended for human consumption. This naturally occurring flavonoid has gained recognition within the scientific community for its potential benefits in various research areas, particularly in the realm of neuroscience and neurobiology.

Key Characteristics

7,8 Dihydroxyflavone is characterized by its remarkable ability to function as a potent small molecule agonist of the brain-derived neurotrophic factor (BDNF) TrkB receptor. This distinctive property makes it a valuable tool for researchers investigating neural regeneration, neuroprotection, and cognitive enhancement.

Research Applications

Researchers have identified several promising applications for 7,8 Dihydroxyflavone. Primarily, it has been employed to investigate neuroprotective and neurotrophic effects, memory enhancement, and cognitive function. This compound has demonstrated its potential in studies related to neurodegenerative diseases, making it an exciting area of research.

Research Benefits

Cognitive Enhancement

Studies involving 7,8 Dihydroxyflavone have revealed its capacity to enhance cognitive function and improve memory retention. This benefit has implications for research into memory-related disorders and age-related cognitive decline.


7,8 Dihydroxyflavone exhibits neuroprotective properties, making it a valuable asset for research aimed at understanding and potentially treating neurodegenerative conditions. It has shown potential in safeguarding neurons from damage and promoting overall neural health.

Neural Regeneration

The compound has demonstrated the potential to stimulate neural regeneration, which is a critical aspect of research focusing on brain injuries and neurodegenerative diseases. It holds promise for aiding the regrowth of damaged or degenerated neurons.


7,8 Dihydroxyflavone is a compelling research compound with applications primarily in the field of neuroscience. Its unique role as a BDNF TrkB receptor agonist has led to research breakthroughs in cognitive enhancement, neuroprotection, and neural regeneration. It is imperative to emphasize that 7,8 Dihydroxyflavone is strictly intended for research purposes and is not suitable for human consumption.


  1. Jang, S. W., Liu, X., Chan, C. B., France, S. A., Sayeed, I., Tang, W., … & Ye, K. (2010). Deoxygedunin, is a natural product with potent neurotrophic activity in mice. PloS one, 5(3), e11528. [Read more]
  2. Castello, N. A., Nguyen, M. H., Tran, J. D., Cheng, D., Green, K. N., & LaFerla, F. M. (2014). 7,8-Dihydroxyflavone, a small molecule TrkB agonist, improves spatial memory and increases thin spine density in a mouse model of Alzheimer’s disease-like neuronal loss. PloS one, 9(2), e91453. [Read more]
  3. Zhang, J. C., Yao, W., Dong, C., Yang, C., Ren, Q., Ma, M., … & Hashimoto, K. (2016). Blockade of 5-HT 6 receptors by SB-271046 enhances basal dopamine release and reverses the impairment of prepulse inhibition in mice induced by 5-HT 2A receptor activation. Psychopharmacology, 233(2), 238-247. [Read more]


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